Education

• The University of Manchester, 2017, PhD, Biophysical Chemistry: Ion Mobility Mass Spectrometry

• The University of Glasgow, 2012, MRes, Proteomics and Cell Technology

• The University of Edinburgh, 2011, MChem, Medicinal and Biological Chemistry

Publications

• The potential of ion mobility mass spectrometry for tuning synthetic host guest systems: A case study using novel zinc(II)dipicolylamine anion sensors November 2015

• The use of ion mobility mass spectrometry to assist protein design: a case study on zinc finger fold versus coiled coil interactions January 2015

• Restriction endonuclease TseI cleaves A:A and T:T mismatches in CAG and CTG repeats February 2013

Sterling Resources

• Monitoring pH stress of biologics August 2023

• Characterisation of a peptide conjugate and impurities July 2023

• High resolution mass spectrometry for impurity profiling April 2023

  Confirmation of structures and generation of potential elemental composition in small molecule active pharmaceutical ingredients

• The use of mass spectrometry to aid ADC development July 2022

  This webinar discusses how Sterling uses mass spectrometry in junction with our traditional techniques to analyse ADCs and other biologics to get the best quality data on these molecules.

• Peptide digestion analysis of an antibody drug conjugate July 2022

• Total antibody quantification of an ADC after plasma incubation July 2022

• Measurement of ADC free drug after plasma incubation July 2022

• Reduced subunit analysis of a PDB based antibody drug conjugate July 2022

• Disulfide bond mapping of a monoclonal therapeutic antibody July 2022

• Measurement of ADC stability in serum via subunit DAR analysis March 2022

• Measurement of ADC stability in plasma via released payload quantitation March 2022

• Peptide digestion analysis of a monoclonal therapeutic antibody March 2022

• Native intact analysis of a cysteine linked antibody drug conjugate March 2022

• Intact mass analysis of a therapeutic monoclonal antibody biosimilar March 2022

• Reduced subunit analysis of a cysteine linked antibody drug conjugate March 2022

• Reduced subunit analysis of a therapeutic monoclonal antibody March 2022

• Mass spectrometry