We deliver comprehensive chemistry services to support your programme and help you proactively overcome challenges in the early drug discovery and development stages of your project’s lifecycle.
Our talented team of PhD organic chemists can handle an array of complex chemistries; offering innovative solutions to meet your programme’s objectives.
We are experts in the synthesis and analysis of small organic molecules and have vast experience in the preparation of stable isotopically labelled molecules and metabolite synthesis. ... Read more
Our state-of-the-art research and development laboratories are home to a range of specialised equipment which enables us to provide non-GMP supply, catering for up to 100g, ideal for projects in their early stages. As part of our integrated network of facilities, our customers also benefit from access to Sterling’s 1,350+ experts and hassle-free technology transfer to its global development and manufacturing facilities as your project scales. This includes our Cramlington site, which is a short distance from Newcastle Biosphere.
Our close proximity and longstanding relationship with Newcastle University also enables access to a range of additional analytical services, including NMR and X-ray crystallography.
Fast Facts
Established in 2002
20 employees
1,442 sq/ft facility
2,100+ molecules
Approved for schedule 1 to 5 controlled substances
Our Newcastle Biosphere facility delivers extensive research and development (R&D) expertise including support to early phase small molecule projects.
Some of our key services include:
- Custom synthesis of small molecules
- Contract research
- Route design, development and optimisation
- Focused compound libraries
- Stable isotope labelling
- Metabolite synthesis
- Non-GMP supply for toxicology studies
- Isolation and identification of unknown impurities
- Process scale up evaluation
- Organometallic catalysis
Our Newcastle Biosphere facility is home to an array of specialised equipment to handle comprehensive analytical work and complex chemistries for R&D projects, including early phase API discovery and development.
Some of the equipment and facilities we have on site at Newcastle Biosphere include:
- New fully equipped R&D labs
- LC-MS (electrospray)
- Analytical and semi-preparative HPLC
- Chiral HPLC
- NMR access (up to 700 MHz) via Newcastle University
- Optical rotation
- Biotage automated chromatography machines
- Biotage microwave reactor
Our Newcastle Biosphere facility is highly experienced in process improvement, which has frequently led to the filing of new process patents by our customers. Our ability to adapt to changing project requirements and deliver focused compound libraries to strict deadlines, makes us the ideal partner to support your patent’s development.
