Milling and Micronisation

Pharmaceutical milling and micronisation to achieve your target particle size

We deliver the milling and micronisation technology to support your API’s physical characteristics for drug product formulation.

Milling and micronisation services at Sterling

Particle size reduction can be critical to optimising your API’s physical properties and ensuring its ability to be properly formulated as a finished drug product. As part of our material science capabilities at Sterling, we offer pharmaceutical milling and micronisation services to achieve your desired particle size distribution at any stage of development.  ... Read more

Our team of specialists work in partnership with you to achieve your required particle size parameters, preparing your API for successful formulation. We have experience meeting particle size requirements with repeatable quality, at both the small and commercial scale.

We are committed to providing our customers full visibility and transparency, enabling them to observe their programmes in motion. Our processing suites are equipped with state-of-the-art camera systems that offer customers the opportunity to view milling operations performed in the Material Science Centre, remotely. Read less

Fast Facts

Flexible equipment:

Our equipment enables us to offer different types of particle size reduction of your API depending on your desired particle size.

State-of-the-art milling suites:

Our Material Science Centre houses four independent processing suites.


Expert teams:

Our specialists will help you develop the particle size reduction strategy best suited to your material and requirements.

Full visibility:

CCTV monitoring enables customers to view milling operations remotely.

State-of-the-art equipment:

We can utilise mechanical milling, micronisation technology, or a combination of both to achieve your required particle size distribution.

Our mechanical milling capabilities enables us to achieve a particle size down to 30 microns. Our equipment offers the flexibility to support different modes of milling, and our team will help determine which approach, or combination of approaches, will achieve your particle size requirements.

Our mechanical milling equipment includes:

  • Two Frewitt Fredrive units with interchangeable heads. One of our units spans three floors of the Material Science Centre and offers containment up to OEB 4. We can utilise these units for hammer, knife, conical, and sieve milling based on your project requirements.
  • Fredrive Lab for milling development that supports hammer, knife, sieve, and pin milling.
  • Fitzpatrick mill that supports hammer and knife milling.

When an even smaller particle size distribution is required, we can utilise micronisation technology. Micronisation of an API, or spiral jet milling, enables us to achieve a particle size down to 2 to 5 microns.

Our micronisation equipment includes:

  • Sturtevant 1” Microniser enables us to micronise small amounts of material, from 50 to 500 grams, at a throughput rate which is governed by the particle characteristics of the supplied API.

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