Nicholas Kramer - Senior Research Scientist

Nicholas Kramer PhD, BS

Senior Research Scientist

Nicholas obtained his Ph.D. in Chemistry from Florida State University in 2017, having studied synthetic methodology and total synthesis of natural products. Following a postdoc at the University of North Carolina at Chapel Hill, he joined Sterling in 2020 as a Research Scientist working on the process development of small molecule APIs. He has since gone on to be promoted to Senior Research Scientist and is now responsible for the continued development of chemical processes in the research and development chemistry services department.

Education

Florida State University, 2017, PhD, Organic Chemistry
Ramapo College of New Jersey, 2012, BS, Biochemistry

Publications

Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis 2022
Interception of the “Bycroft-Gowland” intermediate in the enzymatic macrocyclization of thiopeptides 2020
The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure 2020
Reaction discovery using neopentylene-tethered coupling partners: Oxidative cycloisomeriztions of tethered dienynes 2017
Reaction discovery using neopentylene-tethered coupling partners: methodology and applications of dienyne cyclodimerizations 2017
Six-step synthesis of alcyopterosin A, a bioactive illudalane sesquiterpene with a gem-dimethylcyclopentane ring 2016

Sterling Resources

Design of experiments: An efficient approach to process optimisation April 2024

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