As part of our commitment to innovation, we continue to develop and expand the application of the Jacobsen Cobalt Salen kinetic resolution catalyst technology.

With over 20 years’ experience with this technology, our expert team has optimised the kinetic resolution catalyst to a fourth generation version, delivering better selectivity with lower loading and simpler purification. This means we can access a broader range of chiral molecules with a focus on higher purity and lower cost.

Core capabilities:

  • Ultra low catalyst loading (0.001mol%)
  • Typical e.e. > 99.8%
  • Increased reactivity
  • More robust method with variable raw material input quality
  • Enables the application of fewer reactive nucleophiles compared to kinetic resolution
  • More robust with varying epoxide functional groups

Contact usfor more information on our kinetic resolution services.