Our small molecule pharmaceutical API development facilities can support the development of even the most challenging molecules. We combine health, safety and environment (HSE), quality, production and engineering expertise to ensure we deliver efficient, innovative and sustainable results that are cost-effective from the outset.


Our experienced team of over 100 scientists across our UK and US sites, can develop new processes or optimise existing ones to ensure the most efficient synthetic process is implemented in a robust and scalable way.

From our dedicated development laboratories, our offering includes:

  • 10 and 20 L scale non-GMP manufacturing
  • Hydrogenation suite
  • DoE and QbD support services
  • Multi-block reactors and process intensification
  • Flow chemistry capability
  • Medicinal chemistry services including drug discovery, lead optimisation, route development and parallel and custom synthesis
  • Optimisation and scale-up of existing processes
  • Identification and development of new processes
  • Solid State Chemistry services
  • Hazard evaluation services
  • Full range of supporting and analytical services including LCMS, GCMS, XRPD, ICPMS and NMR
  • Analytical method development, validation and transfer
  • Support for regulatory submissions

Process development

Proof of Concept (POC)

We offer a POC service to our customers to determine the feasibility of a synthetic route and provide our customers with a clearly defined pathway to success.

Quality by Design (QbD) and Design of Experiments (DoE)

We apply our QbD and DOE approaches to generate experimental evidence of critical process parameters and ensure the production of a consistently high-quality product while mitigating risk.

Technology transfer

Our significant technology transfer (TT) experience allows us to efficiently scale-up our customers’ projects from grams to tonnes. Our global, integrated facility network allows us to offer a swift and streamlined TT process from early phase through to commercial batch production.

Drug discovery

We offer a range of drug discovery services including new route development and lead optimisation from our US facility.


We offer a comprehensive range of supporting analytical services to underpin the success of your development programmes. Our scientists deliver robust, transferable methods that are tailored to your phase of development.

Our services include:

  • Method development and method qualification
  • Validation and transfer
  • Elemental risk assessment

Technological innovation

We work closely with a number of academic institutions to explore new technologies that could benefit our customers’ development projects. By creating a technology network with subject matter experts, we remain at the forefront of industry technology and innovation.